Phytochemical Composition, Medicinal Applications, and Pharmacological Insights: A Comparative Review of Rauvolfia serpentina and Rauvolfia tetraphylla
Sapugaskandage Shenya *
Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka.
Dinara Sendanayake
Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka.
Sohani Medis
Department of Medical Laboratory Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka.
Niluka Dlirukshi
Department of Medical Laboratory Sciences, Faculty of Health Sciences, Open University, Sri Lanka.
*Author to whom correspondence should be addressed.
Abstract
Aims: This review article aims to compare the phytochemical profile, therapeutic potential and pharmacological activities of Rauvolfia serpentina and Rauvolfia tetraphylla.
Scope of Review: Review data from published literature and assess about phytochemicals, therapeutic applications and efficacy of Rauvolfia serpentina and Rauvolfia tetraphylla against microorganisms and inflammation comparatively.
Methodology: Research papers and review articles on Rauvolfia serpentina and Rauvolfia tetraphylla were collected and analyzed about phytochemicals, medicinal uses, antibacterial and inflammatory properties.
Summary of Findings: Rauvolfia serpentina and Rauvolfia tetraphylla have many similarities in its phytochemistry such as alkaloids like Reserpine, Ajmaline. They have been used to treat similar diseases and illness conditions like hypertension, psychotic disorders and snake bites.
Conclusion: According to the findings, due to endangered status of Rauvolfia serpentina, Rauvolfia tetraphylla can be used as an ideal substitute and can be used for developing novel antimicrobial and anti-inflammatory drugs with mild side effects. Further investigations are necessary to determine their efficacy.
Keywords: Rauvolfia serpentine, Rauvolfia tetraphylla, phytochemistry, antimicrobial activity, anti-inflammatory activity, alkaloids